Advancements in Topical Treatments for Acne Vulgaris: A Comprehensive Review of Efficacy, Safety, and Patient Satisfaction

Abstract

Acne vulgaris remains a challenging dermatological condition, necessitating a nuanced understanding of the evolving landscape of topical treatments. This literature review examines the multifaceted aspects of topical therapies for acne vulgaris, meticulously examining their efficacy, safety profile, and patient satisfaction. A literature review was conducted using PubMed and Scholar Google, searching the keywords "Acne vulgaris treatments," “Acne vulgaris topical treatments,” "topical acne treatments," "benzoyl peroxide acne treatment," "salicylic acid acne treatment," “topical antibiotics for acne,” “acne antibiotics,” and “acne oral treatment.” A total of 52 articles were screened for this review. Leveraging recent clinical trials, randomized controlled studies, and meta-analyses, this review scrutinizes the mechanisms of action and adverse effects associated with commonly prescribed topical agents, including retinoids, benzoyl peroxide, salicylic acid, and topical antibiotics. Furthermore, emerging trends in combination topical and oral therapies are explored, highlighting the potential for personalized treatment approaches tailored to individual patient needs. By synthesizing current evidence and identifying areas for improvement, this review aims to equip dermatologists with a comprehensive understanding of topical acne treatments, facilitating informed decision-making and enhancing patient-centered care strategies. Our analysis serves as a crucial tool for dermatologists, focusing on a specific understanding of the current landscape of topical treatments for acne vulgaris and empowers clinicians to make informed decisions, thereby enhancing the quality of care and outcomes for patients.