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Abstract
Introduction: Hyperpigmentation is a common skin condition characterized by excess melanin production, resulting in dark patches or spots on the skin. While genetic, sun exposure, and hormonal factors contribute to hyperpigmentation, emerging evidence has demonstrated a potential link between diet and skin pigmentation. This systematic review aimed to investigate the impact of specific nutrients, dietary patterns, and interventions on skin pigmentation disorders.
Methods: A comprehensive literature search was conducted in PubMed, Embase, Scopus and Cochrane using relevant keywords and MeSH terms. Inclusion criteria included manuscripts published within the last ten years, in the English language. Studies encompassed research on the association between diet, nutrition, and hyperpigmentation. Two independent reviewers assessed study eligibility based on predetermined criteria. Data extraction covered characteristics, participant demographics, dietary factors, hyperpigmentation outcomes, and relevant findings.
Results: This systematic review synthesized and analyzed the impacts of diet on hyperpigmentation and assessed the effectiveness of dietary interventions in managing skin pigmentation disorders based on existing literature. Primary outcomes included changes in hyperpigmentation severity, melanin production, and skin color improvement. Secondary outcomes may explore the role of specific nutrients (e.g., antioxidants, vitamins, minerals), dietary patterns (e.g., Mediterranean diet, low glycemic index diet), and potential underlying mechanisms.
Conclusion: This review provides valuable insights into the relationship between diet and hyperpigmentation. Our findings identify dietary strategies or interventions for managing hyperpigmentation and improving skin pigmentation disorders.